35. Purified Proteases

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Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases.

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Dendritic cells (DC) are known to present exogenous protein Ag effectively to T cells. In this study we sought to identify the proteases that DC employ during antigen processing. The murine epidermal-derived DC line Xs52, when pulsed with PPD, optimally activated the PPD-reactive Th1 clone LNC.2F1 as well as the Th2 clone LNC.4k1, and this activation was completely blocked by chloroquine pretre...

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Viral proteases.

Viruses are major pathogenic agents that can cause a variety of serious diseases in humans, other animals, and plants. Due to their clinical and scientific importance, viruses have been under intensive study ever since their first isolation about a century ago. The studies of viruses, their life cycles, and their interactions with the hosts have established many new areas of biological research...

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ژورنال

عنوان ژورنال: Proceedings of the Imperial Academy

سال: 1944

ISSN: 0369-9846,1881-1140

DOI: 10.2183/pjab1912.20.152